国产精品午夜无码av天美传媒-久久久久成人精品免费播放动漫-精品久久久久久无码人妻-热re99久久精品国产99热-国精品无码一区二区三区左线

熱門搜索: 硫酸角質素(KS)ELISA試劑盒(種屬:魚) 白介素6(IL6)ELISA試劑盒(種屬:魚) 魚白介素10(IL10)ELISA試劑盒發貨及時 斑馬魚白介素12BELISA試劑盒發貨及時 兔載脂蛋白B(apo-B)ELISA試劑盒發貨及時 兔孕酮(PROG)ELISA試劑盒發貨及時 兔羥脯氨酸(Hyp)ELISA試劑盒發貨及時 兔抗酒石酸酸性磷酸酶ELISA試劑盒發貨及時 兔晶體蛋白α(Cryα)ELISA試劑盒發貨及時 兔結締組織生長因子ELISA試劑盒發貨及時 兔基質金屬蛋白酶9ELISA試劑盒發貨及時 兔肺表面活性物質相ELISA試劑盒發貨及時 CD206分子ELISA試劑盒(種屬:小鼠) CC趨化因子受體6ELISA試劑盒(種屬:小鼠) 阻抑素(PHB)ELISA試劑盒(種屬:大鼠) 中性內肽酶;腦啡ELISA試劑盒(種屬:大鼠)

技術文章/ Technical Articles

您的位置:首頁  /  技術文章  /  引用大鼠ELISA科研檢測試劑盒的文獻

引用大鼠ELISA科研檢測試劑盒的文獻

更新時間:2023-09-19      瀏覽次數:1357

引用大鼠ELISA科研檢測試劑盒的文獻


文獻收集:

Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3- Mediated Pyroptosis

引用試劑盒:

種屬:大鼠

IL-1β (RJ15465), IL-18 (RJ15463),TNF-α (RJ16622), IL-6 (RJ15478), IL-10 (RJ15453),iNOS(RJ16565) , MDA (RJ15503), ROS(RJ15780) ,CAT(RJ15737),SOD(RJ16691) ,GSHPx(RJ25745) , LDH (RJ16172)

 

638272614877654132225.jpg

IF:7.675


Abstract: Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate NLRP3; thus, the ROS/NLRP3/pyroptosis axis plays a vital role in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI). Therefore, targeting the inhibition of the ROS/NLRP3/pyroptosis axis may be a promising therapeutic tactic for CIRI. Epimedium (EP) contains many active ingredients (ICA, ICS II, and ICT), which have a wide range of pharmacological activities. However, whether EP can protect against CIRI remains unknown. Thus, in this study, we designed to investigate the effect and possible underlying mechanism of EP on CIRI. The results showed that treatment with EP dramatically mitigated brain damage in rats following CIRI, which was achieved by suppressing mitochondrial oxidative stress and neuroinflammation. Furthermore, we identified the ROS/NLRP3/pyroptosis axis as a vital process and NLRP3 as a vital target in EP-mediated protection. Most interestingly, the main compounds of EP directly bonded with NLRP3, as reflected by molecular docking, which indicated that NLRP3 might be a promising therapeutic target for EP-elicited cerebral protection. In conclusion, our findings illustrate that ICS II protects against neuron loss and neuroinflammation after CIRI by inhibiting ROS/NLRP3-mediated pyroptosis.


image.png









微信掃一掃

郵箱:2450868877@qq.com

傳真:86-區號-傳真號碼

地址:上海市楊浦區鐵嶺路32號1519-10室

Copyright © 2025 上海仁捷生物科技有限公司版權所有   備案號:滬ICP備16052159號-1   總訪問量:316135   技術支持:化工儀器網

TEL:17302193538

掃碼加微信
主站蜘蛛池模板: 国产精品推荐手机在线| 久久久www免费人成精品| 中文字字幕人妻中文| 日本va欧美va精品发布| 国产精品久久精品国产| 亚洲成av人片一区二区梦乃| 麻豆国产人妻欲求不满| 日韩人妻无码系列专区| 无遮挡又黄又刺激又爽的视频 | 一本av高清一区二区三区| 国产二级一片内射视频插放| 免费人成视频在线| 制服丝袜中文字幕在线| 精品无码久久久久国产| 亚洲无?码A片在线观看| 好紧好爽免费午夜视频| 国产真实乱子伦视频播放| 好吊妞人成视频在线观看27du| 天天躁日日躁狠狠躁超碰97| 亚洲中文字幕无码爆乳app| 无码人妻精品一区二区三区蜜桃 | 99久久精品免费观看国产| 亚洲综合无码一区二区痴汉| 一本大道伊人av久久综合| 日本japanese丰满少妇| 性xxxx欧美老妇506070| 男女性爽大片视频| 朝鲜女人大白屁股ass| 成人欧美一区二区三区| 成人无码免费一区二区三区| 又色又爽又高潮免费视频观看| 国产精品香蕉在线观看| 婷婷五月综合缴情在线视频| 国产农村乱对白刺激视频| 国产精品丝袜黑色高跟鞋| 久久久无码人妻精品一区| 国产精品av免费观看| 免费中文熟妇在线影片| 色播亚洲视频在线观看| 97精品人妻系列无码人妻| 日本护士毛茸茸高潮|